The Spring Simulation Multi-Conference 2016 (SpringSim'16) brings leading experts in various domains of Modeling and Simulation together. The following symposia are organized under SpringSim'16. Annual Simulation Symposium (ANSS) Communications and Networking Symposium (CNS) High Performance Computing Symposium (HPC) Symposium on Theory of Modeling and Simulation (TMS/DEVS) Agent-Directed Simulation (ADS) Modeling and Simulation in Medicine (M...